Table 4. Sensitivity, specificity of each instrument completed by informants at different cut-off scores for discriminating dementia (normal vs. dementia).
Cut-off score | Normal (n = 200) | Dementia (n = 170) | Sensitivity (95% CI) | Specificity (95% CI) | AUC (95% CI) | |
---|---|---|---|---|---|---|
i-KDSQ-C | 0.92 (0.89–0.95) | |||||
< 9 | 185 | 36 | 0.79 (0.72–0.85) | 0.93 (0.88–0.96) | ||
≥ 9a | 15 | 134 | ||||
< 6 | 158 | 26 | 0.85 (0.78–0.90) | 0.79 (0.73–0.84) | ||
≥ 6 | 42 | 144 | ||||
i-AD8 | 0.93 (0.90–0.95) | |||||
< 3 | 177 | 29 | 0.83 (0.76–0.88) | 0.89 (0.83–0.93) | ||
≥ 3a | 23 | 141 | ||||
< 2 | 161 | 17 | 0.90 (0.84–0.94) | 0.81 (0.74–0.86) | ||
≥ 2 | 39 | 153 | ||||
i-SMCQ | 0.92 (0.89–0.95) | |||||
< 5 | 166 | 21 | 0.88 (0.82–0.92) | 0.83 (0.77–0.88) | ||
≥ 5a | 34 | 149 | ||||
< 6 | 173 | 32 | 0.81 (0.74–0.87) | 0.87 (0.81–0.91) | ||
≥ 6 | 27 | 138 |
AUC = area under the curve, CI = confidence interval, i-KDSQ-C = informant-completed Korean Dementia Screening Questionnaire-Cognition, i-AD8 = informant-completed Alzheimer Disease 8, i-SMCQ = informant-completed Subjective Memory Complaints Questionnaire.
aOptimal cut-off by Youden's index.