Table 2.

Single factor analysis of variance (ANOVA) of ¹¹C-CFT and ¹⁸F-FDG uptake in ROIs between different diagnostic groups.

Test groups	11C-CFT				18F-FDG
	Manual		NeuroQ		NeuroQ
	CN/Cb	Pu/Cb	CN/Cb	Pu/Cb	CN	Pu	MB	Pons	Cb
(1) PD	1.16 ± 0.50	0.69 ± 0.27	1.67 ± 0.36	1.74 ± 0.31	0.93 ± 0.05	1.19 ± 0.06	0.72 ± 0.04	0.65 ± 0.03	0.92 ± 0.04
(2)NC	1.82 ± 0.24	1.98 ± 0.21	2.23 ± 0.36	2.82 ± 0.43	0.96 ± 0.04	1.18 ± 0.04	0.73 ± 0.02	0.66 ± 0.02	0.91 ± 0.03
(3) MSA	1.21 ± 0.52	1.02 ± 0.62	1.74 ± 0.34	1.79 ± 0.35	0.96 ± 0.06	1.15 ± 0.10	0.74 ± 0.02	0.58 ± 0.03	0.71 ± 0.07
(4) ET	2.03 ± 0.21	2.14 ± 0.25	2.50 ± 0.47	3.16 ± 0.49	0.94 ± 0.05	1.18 ± 0.04	0.72 ± 0.02	0.65 ± 0.02	0.90 ± 0.03
Sig.1/2	0.000∗	0.000∗	0.000∗	0.000∗	0.067	0.608	0.186	0.302	0.630
Sig.1/3	1.000	0.577	0.644	0.743	0.092	0.064	0.048Δ	0.000∗	0.000∗
Sig.1/4	0.000∗	0.000∗	0.000∗	0.000∗	0.521	0.631	0.750	0.911	0.318
Sig.2/3	0.030Δ	0.004∗	0.004∗	0.000∗	0.930	0.221	0.520	0.000∗	0.000∗
Sig.2/4	0.284	0.665	0.125	0.059	0.355	0.985	0.430	0.461	0.607
Sig.3/4	0.004∗	0.001∗	0.000∗	0.000∗	0.408	0.266	0.175	0.000∗	0.000∗

PD, Parkinson’s disease, n = 20; NC, normal control, n = 11; MSA, multiple system atrophy, n = 10; ET, essential tremor, n = 8; Manual, the manual method; NeuroQ, NeuroQ method; CN/Cb, ¹¹C-CFT uptake ratio of caudate nuclei to cerebellum; Pu/Cb, ¹¹C-CFT uptake ratio of putamen to cerebellum; CN, ¹⁸F-FDG uptake value of caudate nuclei; Pu, ¹⁸F-FDG uptake value of putamen; MB, ¹⁸F-FDG uptake value of Midbrain; Pons, ¹⁸F-FDG uptake value of Pons; Cb, ¹⁸F-FDG uptake value of cerebellum; ^∗P < 0.01; ^ΔP < 0.05.