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. 2019 Apr 5;13:313. doi: 10.3389/fnins.2019.00313

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Copyright © 2019 Chu, Li, Jiang, Tan, Ji, Zhang, Jin and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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FA supplementation impaired motor and spatial learning in the offspring. (A) Motor behavior of the mice was assessed by the accelerating rotarod (n = 16–18). (B–E) The Morris water maze test is used to assess spatial learning and memory (n = 16–18). During the training phase, (B) the time traveled to reach the platform (latency) were analyzed. Probe trials were performed 1 day after the last training trial. The swimming speed (C), the first latency to reach the platform zone (D), and the crossing number of the platform zone (E) were analyzed. ^∗p < 0.05, ^∗∗ p < 0.01.