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. 2019 Apr 5;10:604. doi: 10.3389/fmicb.2019.00604

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Copyright © 2019 Abdel-Nour, Su, Duncan, Li, Raju, Shamoun, Valton, Ginevra, Jarraud, Guyard, Kerman and Terebiznik.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Lcl oligomerizes through homotypic binding of the R and C domains. (A,B) Surface plasmon resonance sensorgrams for single-cycle injection analysis of the interaction between His-tagged Lcl, His-tagged LclΔR and LclΔC against GST-tagged Lcl immobilized on anti-GST modified Biacore^TM sensor chips (A) and their associated calculated K_D values (B). Plotted values are the average of 3 individual experiments, ^∗ and^∗∗∗ denotes p < 0.05 and p < 0.001, respectively, by one-way ANOVA.