Table 3.

Multivariable Cox proportional-hazard models (upper panel) and logistic regression analysis (lower panel) for the association of variables of interest and short-term (up to 3 months) death and poor functional outcome.

	Model 1			Model 2			Model 3
	(mean of values)			(SD of values)			(Subject-specific baseline values)			(Subject specific rate of changes)
Variable	HR/OR	95% CI	p value	HR/OR	95% CI	p value	HR/OR	95% CI	p value	HR/OR	95% CI	p value
Death up to 3 months (n = 241)
Glucose (mg/dL) (N = 1269)	1.010	1.007–1.013	<0.001	1.005	0.999–1.011	0.100	1.011	1.008–1.015	<0.001	1.043	1.008–1.080	0.017
SBP (mm Hg) (N = 1214)	1.009	0.998–1.021	0.111	1.042	1.020–1.063	<0.001	1.004	0.994–1.015	0.380	0.944	0.872–1.023	0.158
DBP (mm Hg) (N = 1212)	0.987	0.964–1.011	0.289	1.027	0.990–1.065	0.151	0.993	0.972–1.015	0.548	0.842	0.695–1.021	0.081
Temperature (°C) (N = 1246)	1.045	1.001–1.091	0.045	0.987	0.938–1.038	0.611	3.387	2.597–4.418	<0.001	1.914*	1.712–2.141	<0.001
Poor functional outcome at 3 months (n = 668)
Glucose (mg/dL) (N = 1269)	1.003	0.998–1.008	0.219	1.006	0.997–1.016	0.196	1.004	0.998–1.010	0.190	1.046	0.982–1.115	0.161
SBP (mm Hg) (N = 1214)	1.003	0.992–1.014	0.573	1.013	0.987–1.040	0.322	1.007	0.995–1.020	0.259	1.156	1.047–1.277	0.004
DBP (mm Hg) (N = 1212)	1.004	0.981–1.027	0.750	0.978	0.935–1.024	0.345	1.011	0.984–1.040	0.424	1.515	1.168–1.965	0.002
Temperature (oC) (N = 1246)	1.728	1.188–2.51	0.004	1.349	0.578–3.15	0.489	1.775	1.137–2.772	0.012	1.336*	1.036–1.722	0.026

SD: standard deviation.

Adjusted for baseline parameters: age, gender, NIHSS, eGFR, stroke subtype, history of hypertension, diabetes, smoking, dyslipidaemia, coronary artery diseases, TIAs, atrial fibrillation and in-hospital treatment (aspirin, anticoagulation, thrombolysis). Poor functional outcome, mRS > 2..

*Per 0.1°C change.