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. 2018 Mar 16;3(2):174–184. doi: 10.1177/2396987318765824

Table 5.

Improvement in model discrimination and reclassification of multiple measurements of modifiable physiological factors over the best predictive model for short-term death (up to 3 months).a

Discrimination
Reclassification
Continuous NRI
Model Harrell’s C p value IDI coefficient(SE) Among event subjects Amongnon-event subjects Overall (SE) p value
Model 1 0.84 (0.82–0.87)
Model 1 + glucose (mean) 0.85 (0.83–0.87) 0.023 2.2 (0.59)** 3.74 24.00 27.7 (7.2) <0.001
Model 1 + glucose (subject-specific baseline values and rate in changes) 0.85 (0.83–0.87) 0.024 0.1 (0.03)* −8.72 23.34 14.6 (7.2) 0.041
Model 1 + SBP (SD) 0.85 (0.82–0.87) 0.138 1.38 (0.51)* −5.66 27.28 21.6 (7.6) 0.044
Model 1 + temperature (mean) 0.87 (0.84–0.89) <0.001 0.48 (0.2)* 0.6 40.8 41.4 (5.7) <0.001
Model 1 + temperature (subject-specific baseline values and rate in changes)b 0.87 (0.85–0.89) <0.001 0.79 (0.1)** 19.84 37.96 57.8 (7.2) <0.001

IDI: integrated discrimination index; NRI: Net Reclassification Index; SBP: systolic blood pressure; SE: standard error.

aModel 1: Age, gender, NIHSS, eGFR, stroke subtype, history of hypertension, diabetes, smoking, dyslipidaemia, coronary artery diseases, TIAs, atrial fibrillation and in-hospital treatment (aspirin, anticoagulation, thrombolysis).

bPer 0.1°C change.

*Indicates level of statistical significance <0.05.

**Indicates level of statistical significance <0.001.