Table 3.

Univariate Risk of Overall Post–Liver Transplantation Death

Characteristic	HR (95% CI)	P value
Demographic
Sex, female	1.16 (0.43–3.08)	.77
Race, non-Caucasian	1.16 (0.33–4.09)	.81
Age (per year)	1.01 (0.97–1.05)	.71
Non–private insurance	1.97 (0.78–4.97)	.15
Single/divorced/widowed	1.77 (0.66–4.73)	.25
History of comorbid psychiatric disease	0.79 (0.28–2.23)	.66
History of illicit substance abuse	0.37 (0.05–2.79)	.34
History of failed rehabilitation attempt	0.46 (0.13–1.59)	.22
Family history of alcohol use disorder	0.70 (0.26–1.93)	.50
Unemployed immediately before hospitalization	1.00 (0.39–2.54)	1.00
History of alcohol-related legal issues	1.26 (0.47–3.38)	.64
More than 10 drinks/d at presentation	3.17 (1.04–9.67)	.04
Years of heavy drinking	1.01 (0.96–1.06)	.61
Days of pretransplantation abstinence	0.99 (0.98–1.00)	.14
Clinical
Pre-LT corticosteroid use for AH	2.52 (0.90–7.09)	.08
Renal Replacement therapy at LT	0.47 (0.19–1.20)	.12
MELD-Na score at hospitalization	0.97 (0.91–1.04)	.39
MELD-Na score at listing	0.97 (0.88–1.06)	.47
MELD-Na score at LT	0.95 (0.87–1.05)	.32
ΔMELD-Na from hospitalization to LT	1.01 (0.93–1.09)	.85
Maddrey’s score	1.00 (0.98–1.01)	.46
Day-7 Lille score	7.89 (0.45–139.00)	.16
Post-LT alcohol use
Any alcohol use post-LT	3.54 (1.06–11.85)	.04
Sustained alcohol use post-LTa	4.59 (1.45–14.54)	.01

NOTE. Bold type indicates variables significantly associated with increased risk of post-liver transplantation death, with P<.05.

^aSustained alcohol use post-LT was defined as a patient who had any evidence of alcohol use post-LT, and was still drinking at last follow-up.