Table 1.
The significant GO terms downregulated in MS but upregulated in EA or upregulated in MS but downregulated in EA (p < 0.05).
| Domain | GO terms |
|
|---|---|---|
| Down-regulated in MS and Up-regulated in EA | Up-regulated in MS and Down-regulated in EA | |
| BP: | Synaptic vesicle exocytosis | Response to superoxide |
| Acrosomal vesicle exocytosis | Response to steroid hormone | |
| Regulation of neurotransmitter secretion | Mitochondrial transport | |
| Acrosome reaction | Response to glucocorticoid | |
| Insulin secretion | Cellular response to hormone stimulus | |
| Neurotransmitter transport | Response to activity | |
| Circadian rhythm | ||
| Rhythmic process | ||
| MF: | Syntaxin binding | Hydrogen ion transmembrane transporter activity |
| Calcium-dependent protein binding | Oxidative phosphorylation uncoupler activity | |
| Calcium-dependent phospholipid binding | ||
| Clathrin binding | ||
| SNARE binding | ||
| Neurotransmitter transporter activity | ||
| RNA polymerase II regulatory region sequence-specific DNA binding | ||
| CC: | Nucleus | Mitochondrial membrane |
| Synapse | ||
| Extrinsic component of membrane | ||
| Synaptic vesicle membrane | ||
| Perinuclear endoplasmic reticulum | ||