Table 3.
Tumor | HPV-HPV junction positions in HPV16 genome | Deleted length (nt) | Deleted viral genes | Identified HPV-HPV junction sequence |
---|---|---|---|---|
683 | 501 --- 6984 | 6447 | E1a, E2, E4, E5, L2, L1, URRa | AGTATAGTGGTGGAAGTGGGGGGGGTGTGCAAACCGTTTT |
601 | 6204 --- 3689 | 5391 | L2a, E6, E7, URR, E1, E2, E4, E5 | TTCCTTTAGGACGCAAATTTTTACTACAAGCAGGATTGAA |
711 | 1865 --- 7037 | 5172 | E1a, E2, E4, E5, L2, L1, URRa | GACGTGGTCCAGATTAAGTTTACTAAACTACAATAATTCA |
568 | 6680 --- 6924 | 244 | URRa | TAAACTTGTACGTTTCCTGCAGTTCATACATGAACTGTGT |
515 | 1221 --- 7062 | 5841 | E1a, E2, E4, E5, L2, L1, URRa | TTGTAAAGGATTGTGCAACACTAAGGGCGTAACCGAAATCGGT |
532 | 1091 --- 6897 | 5806 | E1a, E2, E4, E5, L2, L1, URRa | TCACAGATGGTACAATGGGCTTCTAAGGCCAACTAAATGT |
676 | 5852 ---6002 | 150 | L1a | TACATATAAAAATACTAACTGGAATTTTGGTCTACAACCT |
624 | 6967 --- 1493 | 2452 | URRa, E6, E7, E1a | TAAATGTCACCCTAGTTCATACATGAACTGTGTAAAGGTT |
aindicates that only partial deletion was found in that viral gene