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. 2019 Apr 11;17:33. doi: 10.1186/s12915-019-0652-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — Canine enteroids uptake exosome-like vesicles secreted from the parasite Ascaris suum. Representative confocal microscope images taken after 24-h incubation with control fluorophore alone (green fluorescent PKH67) or exosome-like vesicles (EV) labeled with PKH67 green fluorescent dye. Enteroids were counterstained with the nuclear marker DAPI (blue fluorescence). Only exosome+ PKH67 group demonstrated green fluorescence within epithelial cells and within the organoid lumen. The merged image shows the intracytoplasmic localization of the PKH67 green fluorescent dye labeled EV obtained from Ascaris suum