Table 1.
General information and clinical characteristics of the subjects.
| Control group(n = 78) | Hypothyroidism group(n = 77) | P value | |
|---|---|---|---|
| Sex (M/F) | 12/66 | 14/63 | 0.641 |
| Age, years | 44.74 ± 13.92 | 41.97 ± 12.70 | 0.198 |
| Height, m | 1.63 ± 0.06 | 1.63 ± 0.07 | 0.925 |
| Weight, kg | 62.68 ± 10.06 | 65.41 ± 9.25 | 0.081 |
| BMI, kg/m2 | 23.76 ± 3.81 | 24.74 ± 3.20 | 0.085 |
| CHOL, mmol/L | 4.94 ± 0.98 | 6.32 ± 1.81 | <0.001 |
| HDL-C, mmol/L | 1.54 ± 0.36 | 1.68 ± 0.47 | 0.033 |
| LDL-C, mmol/L | 2.84 ± 0.72 | 3.58 ± 1.19 | <0.001 |
| TG, mmol/L | 1.18 (0.73–1.56) | 1.49 (0.97–2.29) | 0.006 |
| CK, U/L | 84.00 (68.75–100.00) | 261.00 (125.00–542.50) | <0.001 |
| FBG, mmol/L | 4.90 ± 0.70 | 4.90 ± 0.72 | 0.968 |
| FT3, pg/mL | 2.91 ± 0.42 | 1.73 ± 0.62 | <0.001 |
| FT4, ng/dL | 1.10 ± 0.11 | 0.47 ± 0.11 | <0.001 |
| TSH, uIU/mL | 2.37 ± 1.16 | 81.22 ± 22.96 | <0.001 |
| Irisin, ng/mL | 54.08 ± 25.79 | 44.09 ± 22.24 | 0.011 |
Data are expressed as mean ± standard deviation unless indicated otherwise. TG and CK are shown as the median (upper and lower quartiles). M: male; F: female; BMI: body mass index; CHOL: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; TG: triglycerides; CK: creatine kinase; FBG: fasting blood glucose; FT3: free triiodothyronine; FT4: free thyroxine; TSH: thyrotropin.