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. 2019 Feb 24;47(4):1731–1739. doi: 10.1177/0300060519829991

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© The Author(s) 2019

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — Effect of alteplase treatment on the levels of platelet surface receptors GPIbα, GPVI and αIIbβ3. Following treatment of platelets with different concentrations of alteplase (1, 10, 100 or 200 μg/ml) for 60 min at 37°C, the surface levels of GPIbα, GPVI and αIIbβ3 were measured using flow cytometry and fluorescein isothiocyanate (FITC)-conjugated mouse anti-human CD42b antibody (GPIbα; a), mouse anti-human GPVI antibody (detected using FITC-conjugated goat anti-mouse IgG; b) or FITC-conjugated mouse anti-human CD41a antibody (αIIb) (c). Data presented as mean ± SD.