Fig. 3.

Comparison of pachyvessel diameter and choroidal vascularity change between responders vs. non-responders and non-recurrent vs. recurrent eyes during 1-year follow-up Polygonal lines demonstrate pachyvessel diameter change and bar graphs indicate choroidal vascularity (CV). (Left) Reduction of pachyvessel diameter was significant at 3 months after photodynamic therapy (PDT) in both responders and non-responders (P < 0.001 and = 0.006, respectively, paired t test). CV reduction at 3 months was significant in responders but not in non-responders (P < 0.001 and = 0.728). (Right) In recurrent eyes, pachyvessel diameter increased at recurrence (P = 0.047 compared with a previous measurement), whereas non-recurrent eyes maintained thinning of the pachyvessel until 12 months (P < 0.001, = 0.218, and 0.816 compared with previous measurements, respectively). Pachyvessel at recurrence in recurrent group was thicker compared with that of 6 months and 12 months after PDT in non-recurrent eyes. CV also increased at the time of recurrence in recurrent eyes (P = 0.001 compared with a previous measurement), whereas it decreased continuously in non-recurrent eyes (P < 0.001, = 0.011, and 0.017 compared with previous measurements, respectively). CV: Choroidal vascularity. *Student t test between groups ^†Student t test compared with recurrence group at the time of recurrence. ^‡Repeated-measures analysis of variance interaction for pachyvessel diameter ^§Repeated-measures analysis of variance interaction for CV. Error bar indicates standard error