Mean IOP and mean number of IOP-lowering medications required pre- and post Xen implant at day 1, week 1, month 1, month 3, month 6, month 9, month 12 and month 18, shown with 95% confidence intervals. Comparison of the pre- and postoperative IOP and number of medications at each time point was performed with the paired Student’s t test and Wilcoxon signed rank test respectively (p < 0.05)