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. 2019 Apr 11;23:117. doi: 10.1186/s13054-019-2418-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Reduced in vitro renal and pulmonary endothelial barrier are associated with reduced in vivo microcirculatory perfusion and increased angiopoietin-2 levels. Association between circulating angiopoietin-2 levels and renal (a) and pulmonary (b) endothelial barrier after plasma exposure, microcirculatory perfusion (c), and lactate levels (d). Association between renal (e) and pulmonary (f) endothelial barrier function after plasma exposure and microcirculatory perfusion. Data are presented with a linear regression with 95% CI and tested with a Pearson’s correlation test. CPB, cardiopulmonary bypass; CI, confidence interval