Table 4.
Features of flexible parametric survival models reported by the prognostic model studies
| Features of flexible parametric survival models | n | (%) |
|---|---|---|
| Benefits | ||
| Additional insights of prognostic factors versus other survival analysis models | 1 | (8.3) |
| Compute additional parameter estimates versus other survival analysis models | 1 | (8.3) |
| Extrapolation using the linear tail of the restricted cubic spline | 2 | (16.7) |
| Flexibly fit (/model) the baseline function | 4 | (33.3) |
| Improved model accuracy | 5 | (41.7) |
| Model time-dependent effects | 1 | (8.3) |
| Validation in other settings | 2 | (16.7) |
| No reported benefits | 3 | (25.0) |
| Limitations | ||
| Overfitting | 1 | (8.3) |
| Difficult to interpret models with more than one time-dependent effect | 1 | (8.3) |
| No reported limitations | 10 | (83.3) |