Table 3.

Quality ratings of the measurement properties of the included instruments

	Truth		Discrimination
Instrument	Content Validity	Construct validity	Reliability	Responsiveness	Floor and ceiling effects
SF-36v2 [34–37, 41, 43, 44]
Physical function	+	+	+	+	+
Role physical	–	?	0	+	–
Bodily pain	+	+	0	+	+
General health	n/a	?	0	+	+
Vitality	+	?	0	+	+
Social functioning	+	?	0	+	–
Role emotional	+	?	0	–	–
Mental health	+	?	0	–	+
SF-36 PCS	n/a	?	0	+	+
SF-36 MCS	n/a	?	0	–	+
MOS-20 [33]
Physical function	+	?	?	?	0
Role functioning	–	?	?	?	0
Social functioning	+	?	?	?	0
Mental health	+	?	?	?	0
Health perception	n/a	?	?	?	0
Pain	+	?	?	?	0
AIMS [33]
Mobility	+	?	?	?	0
Physical activity	+	?	?	?	0
Dexterity	+	?	?	?	0
Household activities	–	?	?	?	0
Social activities	–	?	?	?	0
Activities of daily living	–	?	?	?	0
Pain	+	?	?	?	0
Depression	+	?	?	?	0
Anxiety	+	?	?	?	0
GAQ2.0 [34, 41, 43]
Concern overall	+	?	+/−	+	+
Medication side effects	+	?	–	–	+
Unmet treatment need	+	?	–	–	+
Wellbeing during attack	+	?	+	+	+
Concern during attack	+	?	+	–	+
Total GIS	n/a	?	+	+	0
HAQ-DI [15, 32, 33, 37–41, 43]	+	+/−	+	+	+/−
HAQ-II [15, 36, 37]	+	+	+	?	–
TIQ-20 [42]	+	+	?	0	+
RA-WIS [36]	+	+	+	0	–
VAS pain [15, 35]	+	+	?	+	+
Likert pain [15]	n/d	?	?	+	+
NRS pain [15]	n/d	?	0	+	+
VAS PGA [15, 35]	n/a	+	0	+	+
WPAI Physical function NRS [15]	–	?	0	+	+

+, good measurement property with sufficient methodological quality; +/−, Indefinite measurement prope rty with sufficient methodological quality; −, poor measurement property with sufficient methodological quality;?, indeterminate quality of measurement properties because of inadequate methodological quality; 0, no information found in the literature; n/a, not applicable; n/d, not definable due to unavailability of questionnaire item;

AIMS Arthritis Impact Measurement Scales, GAQ 2.0 Gout Assessment Questionnaire 2.0, GIS Gout Impact Scale, HAQ-DI Health Assessment Questionnaire-Disability Index, HAQ-II Health Assessment Questionnaire-II, MOS-20 Medical Outcomes Study 20-item Short Form Health Survey, SF-36v2 Short Form-36 item version 2, TIQ-20 20-item Tophus Impact Questionnaire, RA-WIS Rheumatoid Arthritis-Work Instability Scale, VAS Visual Analogue Scale, NRS Numeric Rating Scale, PGA patient global assessment, WPAI Work Productivity and Activity Impairment