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. 2019 Apr 11;18:133. doi: 10.1186/s12936-019-2769-z

Table 2.

Temperature persistence and parasite clearance

Characteristics Treatment outcome p-value
Artefan® arm
(n = 78)
Coartem® arm
(n = 75)
Temperature persistence (temperature ≥ 37.5 °C)
 On day 0 66 (84.6%) 61 (81.3%) 0.60
 On day 3 1 (1.3%) 0 (0.0%) 0.54
 On day 7 2 (2.9%) 0 (0.0%) 0.25
 On day 14 2 (2.9%) 0 (0.0%) 0.26
 On day 21 1 (1.6%) 0 (0.0%) 0.51
 On day 28 3 (5%) 1 (1.7%) 0.31
Parasite clearance
 Smear positive on day 3 0 0
 Smear positive on day 7 0 0
 Smear positive on day 14 0 (0.0%) 1 (1.1%) 0.71
 Smear positive on day 21 6 (7.7%) 10 (13.3%) 0.42
 Smear positive on day 28 6 (7.7%) 6 (8%) 0.97
Mean hemoglobin concentration (SD)
 Day 3 8.9 (1.5) 8.8 (1.4) 0.96
 Day 7 9.0 (1.4) 9.1 (1.5) 0.73
 Day 14 9.8 (1.3) 9.6 (1.3) 0.43
 Day 21 10 (1.4) 9.8 (1.4) 0.97
 Day 28 10.3 (1.4) 10.4 (1.3) 0.74