Table 3.

CYP2D6 inhibitors^†.

Strong inhibitors	Moderate inhibitors	Weak inhibitors
Bupropion, fluoxetine, paroxetine	Cimetidine, cinacalcet, duloxetine, fluvoxamine	Amiodarone, celecoxib, cimetidine, clobazam, cobicistat, desvenlafaxine, escitalopram, labetalol, ritonavir, sertraline

^†Strong CYP2D6 inhibitors reduce enzyme activity to the point of equivalence with poor metabolism while moderate inhibitors (e.g., duloxetine) reduce enzyme activity by approximately 50% [65].

Data taken from [69].