Fig. 2.

In vivo performance of 4HPR PLGA millicylinder formulation without solubilizers (10% 4HPR + 3% MgCO3). a) 4HPR release in vivo vs. in vitro (in a solubilizing media containing PBS+ 2%Tween), b) in vivo erosion of 4HPR PLGA implants compared to sham implants (PLGA + 3% MgCO3 only), and c) in vivo water uptake in 4HPR PLGA implants and sham PLGA implants. Values represent mean ± SE (n = 3).