Fig. 7.

Pilot studies to assess the effects of 4HPR-PLGA millicylinders (503H + 20% 4HPR + 20% NaDC + 15% MgCO3 + 1% PVP) on established xenograft tumors that were developed by implantation of human OSCC cells (2095sc, 106 in Matrigel) injected into the flanks of nude mice. Relative to the control (drug free) PLGA millicylinder, tumors that were injected with the 4-HPR implants showed reduced growth. (n = 2 control, n = 3 4-HPR PLGA implants).