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. 2019 Apr 5;10:726. doi: 10.3389/fmicb.2019.00726

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Copyright © 2019 Zeineldin, Megahed, Blair, Burton, Aldridge and Lowe.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Principal component analysis (PCA) based on non-phylogenetic Bray–Curtis distance metrics for the overall fecal antimicrobial resistance genes between the control (CONT) and tulathromycin (TUL) piglets. (B) Principal component analysis (PCA) for the overall fecal antimicrobial resistance genes across all samples at different sampling days (0, 5, and 20). The percent variation explained by each component is indicated on the axes. Significance between the two groups was analyzed using PERMANOVA with 9999 permutations and Bonferroni corrected P-values.