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. 2016 Oct 25;2016(10):CD008367. doi: 10.1002/14651858.CD008367.pub3
Date Event Description
6 March 2017 Feedback has been incorporated See Feedback section for comments regarding different interpretations in other reviews of the effects of chlorhexidine on mortality in critically ill patients.
6 March 2017 Amended Edits to Analysis 1.2 and 4.2.
In response to the feedback, review authors decided that mortality data derived from trial flow diagrams in Berry 2011 and Berry 2013 should not be used. This does not change the mortality results: chlorhexidine versus placebo, RR 1.09 (95% CI 0.96 to 1.23).
Removal of Berry 2011 and 2013 mortality data also means no conclusions can be drawn about the effect on mortality of bicarbonate rinse versus water, Listerine versus water or Listerine versus bicarbonate (previous analyses 4.2.6, 4.2.7, 4.2.8).
20 July 2016 New citation required but conclusions have not changed 6 new studies included. 3 previously included studies now excluded. Some changes to Methods (see 'Differences between protocol and review' section).
17 December 2015 New search has been performed Search updated.
27 November 2013 Amended Minor typographical error.