. 2019 Apr 4;25:2452–2478. doi: 10.12659/MSM.915511

Supplementary Table 13.

Comparison of recurrence-free survival between lower prediction value and higher prediction value groups divided by the Cutoff value from the nomogram prediction model.

Sample	Prediction value	Median time	Std. error	95.0% CI for median time		P-value	HR	95.0% CI for HR
Sample	Prediction value	Median time	Std. error	Lower	Upper	P-value	HR	Lower	Upper
Discovery set (n=353)	Lower	61.4	7.906	45.904	76.896	1.35×10⁻⁶	1.997	1.508	2.643
Discovery set (n=353)	Higher	14.0	2.239	9.644	18.422	1.35×10⁻⁶	1.997	1.508	2.643
Replication set (n=740)	Lower	55.6	5.099	45.607	65.593	3.73×10⁻¹⁵	2.079	1.732	2.494
Replication set (n=740)	Higher	12.5	1.087	10.403	14.664	3.73×10⁻¹⁵	2.079	1.732	2.494
Combined set (n=1093)	Lower	56.0	4.332	47.543	64.524	4.10×10⁻²⁰	2.044	1.755	2.381
Combined set (n=1093)	Higher	13.0	1.192	10.664	15.336	4.10×10⁻²⁰	2.044	1.755	2.381
Validation set (n=306)	Lower	56.2	7.680	41.180	71.286	2.57×10⁻⁴	1.751	1.297	2.365
Validation set (n=306)	Higher	16.8	1.877	13.087	20.446	2.57×10⁻⁴	1.751	1.297	2.365
Entire cohort (n=1399)	Lower	56.0	3.944	48.303	63.764	5.42×10⁻²³	1.984	1.732	2.273
Entire cohort (n=1399)	Higher	14.0	1.065	11.913	16.087	5.42×10⁻²³	1.984	1.732	2.273

Owing to failure of genotyping in several of the 5 SNPs for some samples, the number of participants in each set may not equal to the total number. CI – confidence interval; HR – hazard ratio.