Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Mar 29;10:297. doi: 10.3389/fphar.2019.00297

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Shah, Liu, Al Kury, Zeb, Koh, Abbas, Li, Yang, Liu, Jiang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Melatonin protects synaptic protein from ischemic injury. (A) Western blot analysis of SNAP-25 and synaptophysin from ischemic cortex and striatum of vehicle-treated MCAO, melatonin-treated MCAO animals, sham-operated control group, and melatonin treated sham group (n = 7 rats per group). The bands were quantified using ImageJ, analyzed by graph-pad prism-5 software. β-actin was used as control. Densitometric analysis was expressed in arbitrary units as the mean ± SEM for the indicated proteins. (B) Immunofluorescence reactivity of synaptophysin; (n = 7 rats/group). The above data is representation of 3 numbers of experiments. Scale bar = 100 μm and magnification 40×. Synaptophysin was visualized by Alexa-Flour 594. Symbols ^∗ or ^# represent significant difference values p < 0.05, while symbols ^∗∗ and ^## represent p < 0.01 values for significant differences, symbol ^∗∗∗ shows p < 0.001. Symbols ^∗ shows significant difference relative to sham control while ^# shows significant difference relative to MCAO.