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AK23-induced blister formation in vivo is Src- and cortactin-dependent. (A) H.E.-stained serial sections showed that acantholysis induced by AK23 is almost completely blocked by inhibition of Src in wt but not CTTN−/− mice. Scale bar = 100 μm. (B,C) Blister scores for experiments described above (n = 3, #p < 0.05; *p < 0.05 vs. control).
