Table 3.

Partial list of chemical compounds isolated from CR.

Classification	Number	Ingredient name	Reference
Alkaloids	1	Berberine	(Noguchi et al. 1978)
	2	Berberrubine	(Li ZF et al. 2012)
	3	Coptisine	(Wang et al. 2014)
	4	Palmatine
	5	Epiberberine	(Mizuno et al. 1992)
	6	Columbamine	(Ikuta and Itokawa 1989)
	7	Tetradehydroscoulerine	(Chen et al. 2008)
	8	Jatrorrhizine	(Li ZF et al. 2012)
	9	Groenlandicine
	10	Berberastine	(Li ZF et al. 2012)
	11	Worenine
	12	8-Oxyberberine	(Wang et al. 2014)
	13	8-Oxycoptisine
	14	3-Hydroxy-2-methoxy-9,10-methylenedioxy-8-oxyprotoberberine	(Zhao et al. 2010)
	15	8-Oxyepiberberine	(Yang et al. 2014)
	16	8-Oxyberberrubine
	17	(−)-5-Hydroxyl-8-oxyberberine	(Wang et al. 2014)
	18	(+)-5-Hydroxyl-8-oxyberberine
	19	Tetrahydroberberine	(Wang et al. 2014)
	20	8,13-Dioxocoptisine hydroxide	(Yang et al. 2014)
	21	1,3-Dioxolo[4,5-g]isoquinolin-5(6H)-one	(Wang et al. 2007)
	22	Noroxyhydrastinine
	23	Corydaldine	(Ma et al. 2013)
	24	Thalifoline	(Li ZF et al. 2012)
	25	6-([1,3]Dioxolo[4,5-g]isoquinoline-5-carbonyl)-2,3-dimethoxy benzoic acid methyl ester	(Wang et al. 2014)
	26	Berbithine
	27	Coptisonine	(Yang et al. 2014)
	28	Tetrandrine
	29	Obamegine
	30	Magnoflorine	(Tomita and Kura 1956)
	31	Sanguinarine	(Mizuno et al. 1988)
	32	Norsanguinarine
	33	Oxysanguinarine
	34	6-Acetonyl-5,6-dihydrosanguinarine
	35	Chilenine	(Yang et al. 2014)
	36	Z-N-Ferulyltyramine	(Li ZF et al. 2012)
	37	E-N-Feruloyltyramine	(Ma H et al. 2013)
	38	3-Hydroxy-1-(4-hydroxyphenethyl) pyrrolidine-2,5-dione	(Li ZF et al. 2013)
	39	4′-[Formyl-5-(hydroxymethyl)-1H-pyrrol-1-yl] butanoate	(Ma H et al. 2013)
	40	8,9-Dihydroxy-1,5,6,10-β-tetrahydro-2H-pyrrolo[2,1-α]-isoquinolin-5-one	(Li, et al. 2012)
	41	Ehyl-2-pyrrolidinone-5(S)-carboxylate
	42	Methyl-5-hydroxy-2-pyridinecarboxylate
	43	1H-indole-3-carboxaldehyde
	44	Choline	(Chen L et al. 2012)
Lignans	45	Woorenogenin	(Chen et al. 2016)
	46	Woorenoside I	(Yoshikawa et al. 1995)
	47	Longifolroside A	(Meng et al. 2013)
	48	Woorenoside II	(Yoshikawa et al. 1995)
	49	Woorenoside V
	50	Woorenoside III
	51	Woorenoside IV
	52	(+)-Pinoresinol
	53	(+)-Medioresinol
	54	(+)-Pinoresinol glucoside
	55	(+)-Pinoresinol-4,4′-O-β-d-diglucopyranoside	(Yoshikawa et al.1997)
	56	(+)-Syringaresinol glucoside	(Meng et al. 2013)
	57	(+)-Lariciresinol	(Hirano et al. 1997)
	58	(±)-5,5′-Dimethoxylariciresinol	(Li XG et al. 2012)
	59	(+)-5′-Methoxylariciresinol	(Chen L et al. 2012)
	60	(+)-Lariciresinol glucoside	(Chen et al. 2016)
	61	7S, 8R, 8′R-(+)-Lariciresinol-4,4′-O-β-d-diglucopyranoside	(Yoshikawa et al.1997)
	62	Lanicepside A	(Chen et al. 2016)
	63	9-Acetyl lanicepside B
	64	(+)-Isolariciresinol
	65	Isolarisiresinol-9-O-β-d-glucopyranoside	(Li XG et al. 2012)
	66	Woorenoside XI	(Yoshikawa et al.1997)
	67	Cleomiscosin A	(Mizuno et al. 1992)
	68	Aquillochin	( Min et al. 1987)
	69	2,3-bis[(4-Hydroxy-3,5-dimethoxyphenyl)-methyl]-1,4-butanediol
	70	secoisolariciresinol	(Li XG et al. 2012)
	71	Erythro-gaiacylglycerol-8-O-4′-(coniferylalcohol) ether	(Chen L et al. 2012)
	72	Threo-guaiacylglycerol-8-O-4′-(coniferyl alcohol) ether
	73	Woorenoside X	(Yoshikawa et al.1997)
	74	Dihydrodehydrodiconiferyl alcohol	(Li XG et al. 2012)
	75	Wooreno	(Yoshikawa et al.1997)
Simple phenylpropanoids	76	Z-Octadecyl cafeate	(Yang et al. 2014)
	77	E-3-Methoxycinnamic acid	(Ma H et al. 2013)
	78	Ferulic acid	(Li XG et al. 2012)
	79	Ethyl ferulate	(Yoshikawa et al. 1995)
	80	N-Butyl ferulate	(Ma H et al. 2013)
	81	p-Hydroxyphenethyl E-ferulate	(Hirano et al. 1997)
	82	E-3,4-Dimethoxycinnamic acid	(Ma H et al. 2013)
	83	4-O-Feruloylquinic acid	(Li XG et al. 2012)
	84	Methyl 4-O-feruloylquicinate	(Li XG et al. 2012)
	85	Ethyl 4-O-feruloylquicinate	(Ma H et al. 2013)
	86	4-O-Feruloylquinic acid butyl ester	(Li XG et al. 2012)
	87	5-O-Feruloylquinic acid	(Li XG et al. 2012)
	88	Methyl 5-O-feruloylquicinate
	89	Ethyl 5-O-feruloylquicinate
	90	5-O-Feruloylquinic acid butyl ester	(Ma H et al. 2013)
	91	Chlorogenic acid	(Chen L et al. 2012)
	92	Methyl 3-O-feruloylquicinate	(Li XG et al. 2012)
	93	N-Butyl 3-O-feruloylquicinate	(Ma H et al. 2013)
	94	3-(4′-Hydroxyphenyl)-(2R)-lactic acid	(Li XG et al. 2012)
	95	3-(3′,4′-Hydroxyphenyl)-(2R)-lactic acid	(Yahara et al. 1985)
	96	3-(3′,4′-Dihydroxyphenyl)-(2R)-lactic acid-4′-O-β-d-glucopyranoside
	97	Methyl-3-(4′-O-β-d-glucopyranosyl-3′,4′-dihydroxyphenyl)-lactate	(Yoshikawa et al.1997)
	98	Methyl-3,4-dihydroxyphenyl lactate	(Li XG et al. 2012)
	99	Ethyl-3,4-dihydroxyphenyl lactate	(Ma H et al. 2013)
	100	N-Butyl-3,4-dihydroxyphenyl lactate
	101	3-(2,3,4-Trihydroxyphenyl) propanoic acid	(Li XG et al. 2012)
Flavonoids	102	6,8-Dimethyl-3,5,7-trihydroxyfavone	(Meng et al. 2013)
	103	Rhamnetin	(Chen L et al. 2012)
	104	Wogonin
	105	7,4′-Dihydroxy-5-methoxyfavanone	(Min et al. 1987)
	106	2′,4,4′-Trihydroxy-6′-methoxydihydrochalcone
	107	Coptiside I	(Fujiwara et al. 1976)
	108	Coptiside II
	109	Woorenoside XII	(Yoshikawa et al.1997)
Other compounds	110	Limonin	(Wang et al. 2007)
	111	3,4-Dihydroxyphenylethyl alcohol	(Li XG et al. 2012)
	112	3′,4′-Dihydroxyphenethyl alcohol 1-O-β-d-glucopyranoside	(Yahara et al. 1985)
	113	3,5-Dihydroxyphenethyl alcohol-3-O-β-d-glucopyranoside	(Meng et al. 2013)
	114	Protocatechuic aldehyde	(Ma H et al. 2013)
	115	Gentisic acid-5-O-β-d-glucopyranoside	(Yahara et al. 1985)
	116	Apocynol	(Ma H et al. 2013)
	117	1,2-Dihydroxy-benzene	(Li ZF et al. 2012)
	118	Protocatechuic acid	(Meng et al. 2013)
	119	Vanillic acid	(Li ZF et al. 2012)
	120	Vanillic acid-4-O-β-d-glucopyranoside
	121	Protocatechuic acid methyl ester	(Ma H et al. 2013)
	122	Protocatechuic acid ethyl ester	(Wang et al. 2012)
	123	Woorenoside VI	(Yoshikawa et al.1997)
	124	Woorenoside VII
	125	Woorenoside VIII
	126	Woorenoside IX
	127	cyclo-(Phe-Val)	(Li ZF et al. 2012)
	128	cyclo-(Phe-Leu)
	129	β-Sitosterol	(Yang et al. 2014)