Table 2.

Fibrillin-associated candidate proteins co-identification by molecular fishing and native tissue co-purification [25,110].

New Associated Protein Candidates	Known extracellular matrix interactions
Annexins V, II	Ca2+ channels, major components of matrix vesicles with activity stimulated by matrix binding e.g. collagens II and X [112].
Vimentin	Intracellular intermediate filaments interact with matrix indirectly via vimentin-associated matrix adhesions (VAMs) [113].
βig-H3	Matrix molecule with versatile roles in tissue homeostasis; interacts with numerous matrix components [114].
IGFBP3, -7	Modulate IGF in tissue which can be affected by their direct interaction with fibronectin [115].
PAI-1	Protease inhibitor mediates the degradation of matrix [116].