| 1 Adequate pain relief (4 hours after administration) |
4 |
|
Risk Ratio (M‐H, Fixed, 95% CI) |
Subtotals only |
| 1.1 Aspirin 500 mg to 650 mg (A) versus Diflunisal 125 mg (B) |
1 |
65 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.46 [0.84, 2.55] |
| 1.2 Aspirin 500 mg to 650 mg (A) versus Diflunisal 250 mg (B) |
1 |
62 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.77 [0.94, 3.35] |
| 1.3 Aspirin 500 mg to 650 mg (A) versus Diflunisal 500 mg (B) |
1 |
62 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.14 [0.69, 1.88] |
| 1.4 Aspirin 500 mg to 650 mg (A) versus Ibuprofen 300 mg to 400 mg (B) |
1 |
60 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.76 [0.51, 1.15] |
| 1.5 Aspirin 500 mg to 650 mg (A) versus Diclofenac 25 mg (B) |
1 |
102 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.88 [0.63, 1.23] |
| 1.6 Aspirin 500 mg to 650 mg (A) versus Diclofenac 50 mg (B) |
1 |
100 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.79 [0.58, 1.09] |
| 1.7 Aspirin 500 mg to 650 mg (A) versus Diclofenac 100 mg (B) |
1 |
101 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.74 [0.55, 1.01] |
| 1.8 Aspirin 500 mg to 650 mg (A) versus Flurbiprofen 25 mg (B) |
1 |
61 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.30 [0.70, 2.44] |
| 1.9 Aspirin 500 mg to 650 mg (A) versus Flurbiprofen 50 mg (B) |
1 |
58 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.87 [0.51, 1.48] |
| 1.10 Aspirin 500 mg to 650 mg (A) versus Flurbiprofen 100 mg (B) |
1 |
60 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.93 [0.54, 1.60] |
| 2 Adequate pain relief (6 hours after administration) |
5 |
|
Risk Ratio (M‐H, Fixed, 95% CI) |
Subtotals only |
| 2.1 Aspirin 900 mg (A) versus Ibuprofen 300 mg to 400 mg (B) |
1 |
40 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.06 [0.84, 1.34] |
| 2.2 Aspirin 900 mg (A) versus Ibuprofen 900 mg (B) |
1 |
40 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.06 [0.84, 1.34] |
| 2.3 Aspirin 500 mg to 650 mg (A) versus Diflunisal 125 mg (B) |
1 |
65 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.43 [0.85, 2.41] |
| 2.4 Aspirin 500 mg to 650 mg (A) versus Diflunisal 250 mg (B) |
1 |
62 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.69 [0.93, 3.05] |
| 2.5 Aspirin 500 mg to 650 mg (A) versus Diflunisal 500 mg (B) |
1 |
62 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.05 [0.67, 1.66] |
| 2.6 Aspirin 500 mg to 650 mg (A) versus Etodolac 25 mg (B) |
1 |
79 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.49 [0.80, 2.80] |
| 2.7 Aspirin 500 mg to 650 mg (A) versus Etodolac 100 mg (B) |
1 |
79 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.09 [0.63, 1.89] |
| 2.8 Aspirin 500 mg to 650 mg (A) versus Flurbiprofen 25 mg (B) |
1 |
61 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.19 [0.68, 2.09] |
| 2.9 Aspirin 500 mg to 650 mg (A) versus Flurbiprofen 50 mg (B) |
1 |
58 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.78 [0.49, 1.25] |
| 2.10 Aspirin 500 mg to 650 mg (A) versus Flurbiprofen 100 mg (B) |
1 |
60 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.79 [0.49, 1.26] |
| 2.11 Aspirin 500 mg to 650 mg (A) versus Dipyrone 500 mg (B) |
1 |
179 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.90 [0.75, 1.08] |
| 3 Need for additional analgesia (4 hours after administration) |
1 |
|
Risk Ratio (M‐H, Fixed, 95% CI) |
Subtotals only |
| 3.1 Aspirin 500 mg to 650 mg (A) versus Ibuprofen 300 mg to 400 mg (B) |
1 |
60 |
Risk Ratio (M‐H, Fixed, 95% CI) |
11.0 [0.64, 190.53] |
| 4 Need for additional analgesia (6 hours after administration) |
2 |
|
Risk Ratio (M‐H, Fixed, 95% CI) |
Subtotals only |
| 4.1 Aspirin 900 mg (A) versus Ibuprofen 300 mg to 400 mg (B) |
1 |
40 |
Risk Ratio (M‐H, Fixed, 95% CI) |
3.0 [0.13, 69.52] |
| 4.2 Aspirin 900 mg (A) versus Ibuprofen 900 mg (B) |
1 |
40 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 4.3 Aspirin 500 mg to 650 mg (A) versus Flurbiprofen 25 mg (B) |
1 |
61 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.10 [0.07, 16.85] |
| 4.4 Aspirin 500 mg to 650 mg (A) versus Flurbiprofen 50 mg (B) |
1 |
58 |
Risk Ratio (M‐H, Fixed, 95% CI) |
3.0 [0.13, 70.74] |
| 4.5 Aspirin 500 mg to 650 mg (A) versus Flurbiprofen 100 mg (B) |
1 |
60 |
Risk Ratio (M‐H, Fixed, 95% CI) |
3.2 [0.14, 75.55] |
| 5 Maternal drug adverse effects (4 hours after administration) |
2 |
|
Risk Ratio (M‐H, Fixed, 95% CI) |
Subtotals only |
| 5.1 Aspirin 600 mg (A) versus Diflunisal 125 mg (B) |
1 |
65 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 5.2 Aspirin 600 mg (A) versus Diflunisal 250 mg (B) |
1 |
62 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 5.3 Aspirin 600 mg (A) versus Diflunisal 500 mg (B) |
1 |
62 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 5.4 Aspirin 600 mg (A) versus Ibuprofen 400 mg (B) |
1 |
60 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 6 Maternal drug adverse effects (6 hours after administration) |
4 |
|
Risk Ratio (M‐H, Fixed, 95% CI) |
Subtotals only |
| 6.1 Aspirin 900 mg (A) versus Ibuprofen 300 mg to 400 mg (B) |
1 |
40 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.67 [0.46, 6.06] |
| 6.2 Aspirin 900 mg (A) versus Ibuprofen 900 mg (B) |
1 |
40 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.67 [0.46, 6.06] |
| 6.3 Aspirin 500 mg to 650 mg (A) versus Dipyrone 500 mg (B) |
1 |
178 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 6.4 Aspirin 500 mg to 650 mg (A) versus Flurbiprofen 25 mg (B) |
1 |
61 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 6.5 Aspirin 500 mg to 650 mg (A) versus Flurbiprofen 50 mg (B) |
1 |
58 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 6.6 Aspirin 500 mg to 650 mg (A) versus Flurbiprofen 100 mg (B) |
1 |
60 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 6.7 Aspirin 500 mg to 650 mg (A) versus Diflunisal 125 mg (B) |
1 |
65 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 6.8 Aspirin 500 mg to 650 mg (A) versus Diflunisal 250 mg (B) |
1 |
62 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 6.9 Aspirin 500 mg to 650 mg (A) versus Diflunisal 500 mg (B) |
1 |
62 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
