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. 2019 Mar 21;11(6):1733–1744. doi: 10.18632/aging.101865

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Copyright © 2019 Anon-Hidalgo et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY) 3.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of gender, obesity and type 2 diabetes on GDF11 levels. (A) Comparison of serum GDF11 concentrations between males (n=126) and females (n=193). Statistical difference was analyzed by two-tailed unpaired Student’s t test. (B) Comparison of serum GDF11 concentrations between lean (n=49) and obese (n=228) individuals. Statistical difference was analyzed by two-tailed unpaired Student’s t test. (C) Serum GDF11 concentrations in the lean normoglycemic (LN-NG, n=40), obese normoglycemic (OB-NG, n=93), obese with impaired glucose tolerance (OB-IGT, n=46), and obese with type 2 diabetes (OB-T2D, n=47) groups of the whole sample. Statistical differences between groups were analyzed by one-way ANOVA. For the three figures, box represents interquartile range and median inside, with whiskers plotted according to the Tukey method.