Table 2. Univariate analysis of the correlation between GDF11 and other variables, unadjusted and after adjusting for age.
Serum logGDF11 | ||||
Unadjusted correlation | Adjusted correlation | |||
Variable | r | P value | r | P value |
Sex | 0.01 | 0.810 | 0.01 | 0.828 |
Age | -0.16 | 0.005 | — | — |
Weight | 0.11 | 0.059 | 0.08 | 0.168 |
BMI | 0.12 | 0.040 | 0.11 | 0.053 |
Body fat | 0.07 | 0.189 | 0.09 | 0.096 |
FFM | 0.06 | 0.308 | 0.02 | 0.769 |
FFMI | 0.08 | 0.197 | 0.06 | 0.347 |
Waist circumference | 0.10 | 0.076 | 0.11 | 0.055 |
SBP | 0.01 | 0.902 | 0.06 | 0.330 |
DBP | 0.04 | 0.452 | 0.06 | 0.304 |
Glucose | 0.01 | 0.923 | 0.04 | 0.461 |
Insulin | 0.08 | 0.160 | 0.09 | 0.142 |
Glucose 2 h OGTT | 0.02 | 0.776 | 0.05 | 0.425 |
Insulin 2 h OGTT | -0.06 | 0.360 | -0.03 | 0.659 |
HOMA | 0.08 | 0.193 | 0.08 | 0.152 |
QUICKI | -0.04 | 0.484 | -0.07 | 0.243 |
Triglycerides | 0.03 | 0.578 | 0.05 | 0.437 |
Cholesterol | 0.06 | 0.315 | 0.08 | 0.178 |
LDL-cholesterol | 0.07 | 0.252 | 0.08 | 0.184 |
HDL-cholesterol | -0.04 | 0.466 | -0.03 | 0.604 |
Uric acid | 0.01 | 0.823 | 0.01 | 0.824 |
logCRP | 0.13 | 0.106 | 0.12 | 0.144 |
WBC | -0.02 | 0.744 | -0.03 | 0.658 |
ALT | 0.09 | 0.130 | 0.07 | 0.197 |
AST | -0.01 | 0.812 | -0.01 | 0.887 |
AST/ALT ratio | -0.12 | 0.044 | -0.10 | 0.084 |
γ-GT | -0.01 | 0.846 | 0.01 | 0.922 |
Creatinine | 0.05 | 0.387 | 0.08 | 0.182 |
Leptin | 0.11 | 0.076 | 0.11 | 0.062 |
Values are Pearson’s correlation coefficients and associated P values. CRP concentrations were logarithmically transformed for statistical analysis. BMI, body mass index; FFM, fat-free mass; FFMI, fat-free mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; OGTT, oral glucose tolerance test; HOMA, homeostatic model assessment; QUICKI, quantitative insulin sensitivity check index; CRP, C-reactive protein; WBC, white blood cells; ALT, alanine aminotransferase; AST, aspartate aminotransferase; γ-GT, γ-glutamyltransferase. For correlation with gender, male=1 and female=2 was used.