Table 3. Clinical pathological parameters of ccRCC patients with or without mutation/CNV of m6A regulatory genes.
With mutation and/or CNV* | Without mutation and CNV* | P | ||
Age | <=60 | 32 | 218 | 0.325 |
>60 | 25 | 225 | ||
Gender | Female | 26 | 148 | 0.069 |
Male | 31 | 295 | ||
Pathological Stage | I | 36 | 206 | 0.123 |
II | 7 | 48 | ||
III | 8 | 113 | ||
IV | 6 | 73 | ||
Discrepancy | 0 | 3 | ||
Historical Grade | G1 | 5 | 6 | <0.001 |
G2 | 33 | 175 | ||
G3 | 14 | 182 | ||
G4 | 4 | 74 | ||
x | 1 | 4 | ||
N/A | 0 | 2 | ||
T stage | T1 | 36 | 212 | 0.104 |
T2 | 8 | 57 | ||
T3 | 12 | 164 | ||
T4 | 1 | 10 | ||
N stage | N0 | 25 | 201 | 0.683 |
N1 | 1 | 17 | ||
Nx | 31 | 225 | ||
M stage | M0 | 51 | 353 | 0.133 |
M1 | 6 | 71 | ||
Mx | 0 | 19 |
*With mutation or CNV: Cases have mutant or CNV or mutant+CNV, confirmed through TCGA database. Without mutant and CNV: Cases with neither mutant nor CNV, confirmed through TCGA database. Ambiguous variables (Nx, Mx, N/A, discrepancy and Gx) were excluded from chi-square test or non-parametric test