Table 1. HPLC detection of the effect of CDKN2B-AS1 on cholesterol level in THP-1 macrophage-derived foam cells.
Group | TC (μg/mg cell protein) | FC (μg/mg cell protein) | CE (μg/mg cell protein) | CE/TC (%) |
oe-NC | 465.14 ± 12.34 | 188.22 ± 10.25 | 298.24 ± 14.05 | 64.10 |
oe-CDKN2B-AS1 | 289.21 ± 11.02a | 119.83 ± 9.32 a | 162.79 ± 13.05 a | 56.38 |
Note: TC, total cholesterol; FC, free cholesterol; CE, cholesterol ester; a, p < 0.05 vs. the oe-NC group; the measurement data is expressed in the form of mean ± standard deviation and analyzed by unpaired t-test, the experiment was repeated 3 times; THP-1, the human monocytic leukemia cell line; NC, negative control; CDKN, cell-dependent kinase inhibitor.