1 Primary outcome: subjective symptom score (mean) |
3 |
146 |
Std. Mean Difference (IV, Random, 95% CI) |
0.44 [0.11, 0.78] |
1.1 Oral |
2 |
85 |
Std. Mean Difference (IV, Random, 95% CI) |
0.33 [‐0.11, 0.77] |
1.2 Topical |
1 |
61 |
Std. Mean Difference (IV, Random, 95% CI) |
0.59 [0.08, 1.11] |
2 Primary outcome: subjective symptom score (AUC) |
2 |
|
Std. Mean Difference (IV, Random, 95% CI) |
Subtotals only |
2.1 Oral |
2 |
260 |
Std. Mean Difference (IV, Random, 95% CI) |
0.11 [‐0.14, 0.35] |
3 Secondary outcome: objective NAR (mean) |
2 |
332 |
Std. Mean Difference (IV, Random, 95% CI) |
0.39 [‐0.22, 0.99] |
3.1 Oral |
1 |
230 |
Std. Mean Difference (IV, Random, 95% CI) |
0.11 [‐0.14, 0.37] |
3.2 Topical |
1 |
102 |
Std. Mean Difference (IV, Random, 95% CI) |
0.74 [0.23, 1.25] |
4 Secondary outcome: objective NAR (AUC) |
2 |
|
Std. Mean Difference (IV, Random, 95% CI) |
Subtotals only |
4.1 Oral |
2 |
260 |
Std. Mean Difference (IV, Random, 95% CI) |
0.44 [‐0.32, 1.20] |