Table 1. Number of start sites and SNPs in direct vicinity of TSS and CSS.
| TSS | CSS | |||||
|---|---|---|---|---|---|---|
| RefSeq | RefSeq | HEK293 | ||||
| 1000 Genomes | GoNL | 1000 Genomes | GoNL | 1000 Genomes | GoNL | |
| Start sites harboring SNPs | 3,777 | 2,681 | 3,319 | 2,277 | 1,276 | 838 |
| SNPs in these start sites | 4,472 | 3,043 | 3,819 | 2,519 | 1,487 | 942 |
We considered RefSeq and HEK293 genes as well as SNPs from the 1000G and GoNL project. Thereby, we investigated genes with at least one SNP in this sequence window. For the CSS, we considered AUG as start site for the RefSeq dataset and alternative AUG and all near-cognate codons for the HEK293 dataset.