Fig 3. Representative traces of EPSCs for Control (upper) and PostC (lower) groups during pre-ischemic, ischemic and reperfusion periods.

In each trace, EPSCs caused by synaptic glutamate releases are observed as transient downward deflections (inward currents). For both Control and PostC groups, the occurrence of EPSCs began to increase apparently 7 min after ischemic perfusion. In the traces of Control group, an explosive increase in EPSC frequency was seen 2 min after reperfusion. On the other hand for PostC group, increased occurrence of EPSCs was receding to pre-ischemic level immediately after reperfusion.