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. 2019 Apr 12;14(4):e0215391. doi: 10.1371/journal.pone.0215391

Fig 3. Endogenous expression of TREK-like current in the lung cancer LX22 and BEN cells.

Fig 3

After whole-cell access was made from LX22 and BEN cells, outward rectified currents were evoked by the step pulses indicated as protocol (E). (A and B) LX22 cells expressed currents resistant to 5 μM ML365 and sensitive to bupivacaine, which were similar to TREK-1 current. (C and D) BEN cells also expressed 0.3 mM bupivacaine-sensitive current. (F and G) I-V relationship of the whole cell current expressed in LX22 and BEN cells. The I-V relationship indicates the outward rectification of the current and sensitivity to bupivacaine.