Skip to main content
. Author manuscript; available in PMC: 2020 Apr 12.
Published in final edited form as: Circ Res. 2019 Apr 12;124(8):1146–1148. doi: 10.1161/CIRCRESAHA.119.314844

Components to consider when performing a high-throughput screen on human pluripotent stem cell-derived cardiomyocytes.

Components to consider when performing a high-throughput screen on human pluripotent stem cell-derived cardiomyocytes.

Modern techniques allow for a plethora of different parameters to consider when setting out to perform a high throughput screen including: cellular model, type of screen and endpoint functional measurements. Choosing the optimal conditions will depend on the disease/biological perturbation being studied which, will dictate the desired functional measurement to record and whether the cell line will require modifications to accommodate the functional measurement.