. Author manuscript; available in PMC: 2020 Feb 28.

Published in final edited form as: J Control Release. 2019 Jan 21;296:225–231. doi: 10.1016/j.jconrel.2019.01.025

Table 1.

Volumes of fibrotic tissues in lungs of Tg(FABPCFTR)1Jaw/J homozygote/homozygote bi-transgenic mice before and after treatment. Mice were treated twice per week within four weeks by inhalation with nanostructured lipid carriers containing lumacaftor and ivacaftor. Means ± SD are shown.

Tissues	Untreated animals (mm³)	Treated animals (mm³)
Lung volume	363 ± 92	335 ± 103
Volume of fibrotic tissues	183 ± 55	9 ± 39^*

P < .05 when compared with non-treated animals.