Table 1.

Baseline characteristics of women in the NIH-AARP cohort by baseline MetS (N=94,555) ^a

	Overall	MetS		P-values
		Yes	No
	N (%)b	N (col %)	N (col %)
Sample size	94,555	4,956 (5.24)	89,599 (94.76)
Race/Ethnicity
White	90,753 (95.98)	4,630 (93.42)	86,123 (96.12)	<0.0001
Black	3,802 (4.02)	326 (6.58)	3,476 (3.88)
Age at entry (years)
50–59	35,805 (37.87)	1,579 (31.86)	34,226 (38.20)	<0.0001
60–69	55,638 (58.84)	3,178 (64.12)	52,460 (58.55)
70–79	3,112 (3.29)	199 (4.02)	2,913 (3.25)
Education
< High school	4,058 (4.29)	255 (5.15)	3,803 (4.24)	<0.0001
High school or GED	33,226 (35.14)	1,934 (39.02)	31,292 (34.92)
Some college	24,563 (25.98)	1,294 (26.11)	23,269 (25.97)
>= College	32,708 (34.59)	1,473 (29.72)	31,235 (34.86)
Menopausal status
Pre-menopausal	3,693 (3.91)	164 (3.31)	3,529 (3.95)	0.025
Post-menopausal	90,662 (96.09)	4,785 (96.69)	85,877 (96.05
BMI (kg/m2)
Normal BMI	43,546 (46.05)	449 (9.06)	43,097 (48.10)	<0.0001
Overweight or obese	51,009 (53.95)	4,507 (90.94)	46,502 (51.90)
Current hormone therapy
Yes (%)	44,387 (46.94)	1,999 (40.33)	42,388 (47.31)	<0.0001
Family history of breast cancer
Yes (%)	11,949 (12.64)	617 (12.45)	11,332 (12.65)	0.700
Hormone receptors
ER+/PR+	2,995 (71.29)	167 (75.23)	2,828 (70.03)	0.258
ER+/PR−	587 (13.97)	21 (9.46 )	566 (14.02)
ER−/PR−	619 (14.73)	31 (13.96)	588 (14.56)
High WC (%)	22,919 (34.87)	4,776 (96.37)	18,143 (29.86)	<0.0001
High cholesterol (%)	51,324 (54.28)	3,870 (78.09)	47,454 (52.96)	<0.0001
High blood pressure (%)	33,518 (35.45)	4,624 (93.30)	28,894 (32.25)	<0.0001
High fasting glucose (%)	5,819 (6.15)	2,072 (41.81)	3,747 (4.18)	<0.0001
Smoking (%)	51,476 (54.44)	2,577 (52.00)	48,899 (54.58)	0.0004

P values are from Chi-square test or Fisher exact test. Abbreviations: BMI, body mass index; GED, general education development; Ref, reference; WC, waist circumference

^aN=sample size.

^bN (%)=count (percent).