Skip to main content
. Author manuscript; available in PMC: 2020 Jan 4.
Published in final edited form as: Circ Res. 2019 Jan 4;124(1):79–93. doi: 10.1161/CIRCRESAHA.118.313854

Figure 2. Effect of cardiac myocyte-specific ATF6 gene deletion in hearts of mice subjected to free wheel exercise.

Figure 2.

A, Protocol for AAV9 administration to ATF6fl/fl mice and free wheel exercise. B, Immunoblot of LV extracts from Con or ATF6 cKO mice. C, mRNA levels for ATF6 target genes determined by qRT-PCR. D, Heart weights/tibia lengths (HW/TL). E, mRNA levels for fetal genes determined by qRT-PCR. F, ICF analysis of mouse heart sections for laminin (green). Data are mean ± SEM. *P≤0.05, **P≤0.01, #P≤0.001. Echocardiography details are in Online Table II.