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. Author manuscript; available in PMC: 2020 Apr 15.
Published in final edited form as: Arch Biochem Biophys. 2019 Feb 22;665:36–45. doi: 10.1016/j.abb.2019.02.014

Figure 2. Sequence alignment of PRMT7 Double E and THW loops.

Figure 2.

Sequences from humans, mice, nematode worms, and trypanosome PRMT7 have been aligned. Critical glutamate residues that flank the Double E loop are highlighted in red boxes. Acidic residues that direct substrate specificity in human, mouse, and worm PRMT7 are highlighted in cyan boxes. The sequences for substrate stabilizing ‘THW’ loops are also represented.