Figure 3. Overall Crystal structures of PRMT7 from a protist (Trypanosoma brucei, TbPRMT7), a nematode worm (Caenorhabditis elegans, CePRMT7), and a mammal (Mus musculus, MmPRMT7).
A) Crystal structure of TbPRMT7 (PDB: 4M38) as a homodimer; one monomer is colored raspberry and the other light blue. The dimerization arms are indicated in the black boxes. B) Crystal structure of CePRMT7 (PDB: 3X0D) in pale green; the Zn-finger like domain is boxed in red and the Zn2+ ion is shown as a blue sphere. C) Crystal structure of MmPRMT7 (PDB: 4C4A) in gray; the Zn-finger like domain is boxed in red and the Zn2+ ion is shown as a blue sphere.