Table 2:

Cortical thickness measurements in the ipsilateral region surrounding focal areas of leptomeningeal contrast enhancement and in the contralateral region^a

	Entire Cohort (80 LMCE Foci)				Patients with RRMS (55 LMCE Foci)				Patients with SPMS (25 LMCE Foci)
Dilations	Ipsilateral	Contralateral	Pct. Diff.	P/FDR-P	Ipsilateral	Contralateral	Pct. Diff.	P/FDR-P	Ipsilateral	Contralateral	Pct. Diff.	P/FDR-P
5	2.043 (.515)	2.149 (.556)	−5.06	.07/.187	2.031 (.534)	2.212 (.567)	−8.53	.005/.04b	2.070 (.480)	2.000 (.510)	3.44	.562/.823
10	2.063 (.437)	2.160 (.476)	−4.59	.016/.128	2.099 (.455)	2.211 (.501)	−5.20	.011/.044b	1.979 (.387)	2.039 (.396)	−2.99	.493/.823
15	2.088 (.411)	2.153 (.413)	−3.07	.039/.156	2.141 (.414)	2.208 (.432)	−3.08	.055/.147	1.964 (.383)	2.023 (.339)	−2.96	.384/.823
20	2.114 (.286)	2.136 (.385)	−1.04	.409/.554	2.167 (.394)	2.196 (.395)	−1.33	.365/.417	1.989 (.342)	2.000 (.325)	−.55	.895/.895
25	2.116 (.362)	2.131 (.368)	−.71	.485/.554	2.167 (.376)	2.194 (.377)	−1.24	.306/.408	1.996 (.301)	1.983 (.306)	0.65	.749/.856
30	2.113 (.348)	2.131 (.354)	−.85	.342/.554	2.162 (.363)	2.195 (.361)	−1.51	.137/.274	1.997 (.284)	1.980 (.291)	0.85	.617/.823
35	2.115 (.338)	2.127 (.342)	−.57	.483/.554	2.165 (.353)	2.190 (.347)	−1.15	.191/.306	1.998 (.273)	1.977 (.284)	1.06	.509/.823
40	2.117 (.327)	2.120 (.332)	−.14	.882/.882	2.168 (.341)	2.180 (.336)	−.55	.529/.529	1.998 (.261)	1.979 (.282)	0.95	.485/.823

Note:—Pct. Diff. indicates percentage difference; FDR, false discovery rate.

Ipsilateral and contralateral columns represent mean (standard deviation) cortical thickness measures in millimeters.

^aPaired t tests comparing the ipsilateral and contralateral regions were used to calculate P values. The Benjamini-Hochberg procedure was used to control the false discovery rate.

^bCorrected P values < .05.