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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Hepatology. 2019 Mar 18;69(5):1931–1945. doi: 10.1002/hep.30487

Figure 6. A fully penetrant Arid1a; Pten double KO mouse model shows increased response to SREBP-1c inhibition.

Figure 6.

A. Representative gross images of wild-type and Arid1a/Pten double KO livers.

B. Final body weights of mice given either regular chow or CAT-2003 diet (n = 6,8; 5,5; 9,8; 4,5).

C. Liver weights of mice given either regular chow or CAT-2003 diet.

D. Liver weight/body weight ratio of mice given either regular chow or CAT-2003 diet.

E. Western blot for SREBP1 in WT and double KO mice on both regular chow and CAT-2003 diet.