. Author manuscript; available in PMC: 2020 Apr 1.

Published in final edited form as: Alzheimers Dement. 2019 Feb 15;15(4):506–514. doi: 10.1016/j.jalz.2018.12.008

Table 1.

Baseline Characteristics (N=200)

Variable Mean (SD)	aMC (n=116)	Non-MC (n=84)	P values
Age, mean	34.4 (8.6)	34.9 (8.2)	0.69
Female, n (%)	64 (55.2)	46 (54.8)	0.95
APOE ε4+, n (%)	33 (28.7)	22 (26.2)	0.72
CSF Aβ₄₂, pg/mL	379.0 (175.3)	440.6 (146.6)	0.01
CSF Total Tau, pg/mL	81.8 (44.7)	53.9 (22.7)	<0.0001
CSF Ptau, pg/mL	47.9 (27.3)	29.0 (9.4)	<0.0001
PIB Cortical SUVR	1.57 (0.69)	1.03 (0.06)	<0.0001
MRI Precuneus Thickness	4.73 (0.26)	4.78 (0.24)	0.16
MRI Hippocampus Volume	8898.6 (976.1)	8946.9 (758.9)	0.069
FDG Cortical SUVR	1.71 (0.13)	1.71 (0.14)	0.89
PSEN1, n (%)	84 (72.4)	55 (65.5)	0.43
PSEN2, n (%)	14 (12.1)	10 (11.9)
APP, n (%)	18 (15.5)	19 (22.6)

aMC: asymptomatic mutation carriers, Non-MC: mutation non-carriers