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Enhanced ECM in self-assembled constructs with the addition of exogenous LOXL2 and LINK proteins. A) At 4 weeks, all groups produced uniform, flat constructs. Ruler = 1 mm. B) Histological staining showed increased picrosirius red birefringence and safranin O staining in +LINK, +LOX, and +LOX+LINK groups over control. Scale bar = 200 μm.
