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. Author manuscript; available in PMC: 2020 May 22.
Published in final edited form as: Nat Prod Rep. 2019 May 22;36(5):698–713. doi: 10.1039/c8np00075a

Figure 15.

Figure 15.

A. Reactions catalyzed by LepI in leporin C biosynthesis. B. Summary of cascade of LepI-catalyzed reactions. C. Ambimodal transition state structures and asymmetrical bifurcating PES for the formation of leporin C and DA-1 from (E)-QM.