Table 1.

Baseline characteristics of the study cohort

	Controls			Exercise
	APOE ε4 noncarriers	APOE ε4 carriers	P value	APOE ε4 noncarriers	APOE ε4 carriers	P value
n	21	72 (27 homozygotes)		34	72 (27 homozygotes)
Gender			0.45∗			0.23∗
Males, n (%)	11 (52.4)	41 (56.9)		17 (50)	43 (59.7)
Females, n (%)	10 (47.6)	31 (43.1)		17 (50)	29 (40.3)
Age, years†	68.0 (8.8)	72.5 (6.5)	0.01‡	67.9 (9.1)	70.8 (6.4)	0.06‡
MMSE†	25.0 (3.6)	23.9 (3.9)	0.27‡	24.4 (3.5)	23.6 (3.3)	0.26‡
Education, years†	11.5 (2.9)	11.9 (2.7)	0.55‡	12.0 (2.9)	11.9 (2.6)	0.83‡

P values are APOE ε4 carriers versus APOE ε4 noncarriers. Bold value denotes statistical significance P < 0.05.

^∗Chi-squared test.

^†Given as mean ± (standard deviation).

^‡Independent t-test.