Figure 8.

GGCX Gene Mutations in Infertile Male Patients with Asthenozoospermia

(A) The association between genotypes of GGCX rs699664 and male infertility was assessed in 199 infertile patients with asthenozoospermia and 110 fertile controls under the recessive model. In this the GGCX rs699664 is assumed allele T recessive and a one-sided p < 0.05 was considered to be significant.

(B) The location of rs699664 is on the eighth exon of GGCX gene with the single nucleotide variation from C (green) to T (red), which results in a residue change from arginine³²⁵ (R, green) to glutamine³²⁵ (Q, red).